Sodium clodronate (as tetrahydrate). Manufacturers of Clodronate in Pakistan. It is used to treat hypercalcemia (high blood calcium) for people who have cancer. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. inflamação aguda do estômago ou intestino; diminuição da função renal. Bonefos (clodronate) is a non-amino bisphosphonate intended to reduce the occurrence of bone metastases in the post-surgical (adjuvant) treatment of breast cancer patients. DA = Draining area of lymph node. LEGENDS: AL = Alveoli in lung. refrigeração (2-8°C): 24 horas. Brands / Trade Names of Clodronate. MF: CH2Cl2O6P2Na2, MW: 288.86. Macrophage Depletion Kit (Mannosylated) Dermatológico: hipersensibilidade na pele. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Lipid composition: phosphatidylcholine and cholesterol. Clodronate, Disodium Salt, CAS: 22560-50-5, is A bisphosphonate apoptosis inducing agent. It is also called Bonefos, Clasteon, and Loron 520 Company: Berlex, Inc. Genérico: não clodronato dissódico tetraidratado equivalente a clodronato dissódico Uso oral. Previous Drug Generic - Next Drug Generic. Diluente: Cloreto de Sódio 0,9% ou Glicose 5%. Mayo Clinic does not endorse companies or products. This medicine is available only with your doctor's prescription. 1997 Oct 15;80(8 Suppl):1691-5. Injetável (solução) 1500 mg/25 mL: Bonefós Injetável (solução) 300 mg/5 mL: Bonefós O que é medicamentos C. setTimeout("$('adwords').hide();", 10000); classificação não disponibilizada; não usar. Reúne recursos indispensáveis e conteúdos de ponta contextualizados à realidade brasileira, sendo a melhor ferramenta de consulta para tomada de decisões rápidas e eficazes. It is used to stop bone loss. Generic name: clodronate. You may have sodium clodronate for 1 of the following reasons: to treat high blood calcium (hypercalcaemia) •com 1 copo cheio de água, em jejum, pelo menos 30 minutos antes do café da manhã. Kanis JA(1), McCloskey EV. It is a capsule that you take by mouth. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. Drug information provided by: IBM Micromedex. Clodronate is predicted to decrease the effects of parathyroid hormone. It is also used to treat the increased amount of calcium in the blood (hypercalcemia) that may occur with some kinds of cancer. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SODIUM CLODRONATE. Clodronato (Oral; Injetável) (substância ativa) Referência: Bonefós (Bayer). Sodium clodronate (Bonefos, Clasteon, Loron) Sodium clodronate is a type of bisphosphonate. •doses em termos de Clodronato dissódico. Clodronate. Take this medication 1 to 2 hours (depending on your brand) before or 1 to 2 hours after taking any products that contain aluminum, calcium, iron, magnesium, or zinc. Clodronate has been extensively used in patients with advanced breast cancer, and is generally well tolerated. Portions of this document last updated: Feb. 01, 2020. Patients must be adequately hydrated before treatment and renal function must be monitored. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. For SODIUM CLODRONATE. Site designed by Pharma Professional Services and developed by Hasan Computing Systems. (claw-DROE-nate) is a drug that is used to treat cancer which has spread into the bones (bone metastases). Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Treatment for: Breast Cancer, Adjuvant. This site complies with the HONcode standard for trustworthy health information: verify here. Clodronate sodium, also called clodronate disodium, is the disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. hipercalcemia devido a tumores malignos ou metástases ósseas; osteólise (dissolução do osso) devido a metástase de tumores sólidos (câncer de mama, próstata ou tireoide) ou devido a neoplasia sanguínea (mieloma múltiplo). Severity of interaction: Moderate Evidence for interaction: Study. Copyright © 2021 IBM Watson Health. Clodronate molecules are encapsulated in small MLV liposomes for superior activity, physical and chemical stability, and convenience of use and handling. GU = Gut (intestines) Each capsule contains the equivalent of … You might have it as a treatment for a number of cancers that affect the bones such as myeloma and secondary breast cancer. Clodronic acid is approved for human use in Canada and Australia, the United Kingdom, where it is marketed as Bonefos, Loron, Clodron and in Italy as Clasteon, Difosfonal, Osteostab and several generics. It is used to treat high calcium levels in patients with cancer. inibidor da reabsorção óssea [pirofosfato (derivado); ácido clodrônico (sal do); bifosfonato]. • doses em termos de Clodronato dissódico. A dose máxima diária é de 3200 mg. A duração do tratamento é, em geral, de 6 meses. Clodronate is not metabolised and most of the dose appears in the urine within a few days. CLODRONATO ABC Active Ingredient Clodronate 100 mg/3.3 ml injectable solution - 6 ampoules 100 mg/3.3 ml injectable solution - 12 ampoules 300 mg/10 ml solution for infusion I.V. Special pediatric considerations are noted when applicable, otherwise adult provisions apply. The bad news is that clodronate is not directly available in the United States. Back to top. Bonefos Bayer, United Kingdom; Bayer, Tunisia; Er-Kim, Turkey; IFET, Greece Purified talc, calcium stearate, anhydrous colloidal silica, lactose, gelatin, purified water, iron oxide red, iron oxide yellow, Tekprint SW-9008 black ink and titanium dioxide. For Adult. Adverse reactions include renal insufficiency and hypocalcaemia. 12 Equine Key Opinions Leaders in English Performance, Western Performance, Cancer. inibe a reabsorção óssea que leva a aumento do cálcio no sangue. Descriptions. Volume: 500 mL. Name of the medicine. Volume: 500 mL. dados não disponibilizados; não amamentar. Bulk solution: phosphate buffered saline (20mM sodium phosphate, 09wt% NaCl), pH 7.0-7.5 temperatura ambiente (15 - 25°C): 24 horas. Bonefos [DSC]; Clasteon. Tribo™ Human IFN gamma ELISA Kit; Tribo™ Human β2-microglobulin ELISA Kit; Human TNFꭤ ELISA kit; 1 step and 1hr; Fast Human TGF-β1 ELISA Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Clodronic Acid (Oral Route, Injection Route), FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Clodronate Synthesis Reference No information avaliable Hematológico: diminuição do cálcio no sangue. 1600 mg por dia, em dose única. Osteolytic lesions, hypercalcaemia and bone pain associated with skeletal metastases in patients with breast cancer or multiple myeloma. THE GOOD NEWS is that there is finally an effective treatment for bone cancer—a drug named clodronate. What do I need to tell my doctor BEFORE I take this drug? Clodronate, Disodium Salt - CAS 22560-50-5 - Calbiochem 1 Product Result | Match Criteria: Product Name All products: If you have an allergy to clodronate … Estabilidade após diluição com Cloreto de Sódio 0,9% ou Glicose 5%. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. EY = Eye. 1.6 g daily in 1–2 divided doses, then increased if necessary up to 3.2 g daily in 2 divided doses. Excipients Capsules. Many drugs have more than one name and, therefore, the same drug may be listed more than once. O MedicinaNET é o maior portal médico em português. Clodronate (clodronate disodium, Bonefos®) is a non-nitrogen-containing bisphosphonate that inhibits osteoclast activity, and thereby inhibits bone resorption. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. The terminal elimination half-life may exceed a year as clodronate bound to bone is slowly released. •interromper o tratamento se ocorrer comprometimento da função dos rins. All rights reserved. Both types of Clophsome ® are offered in the standard suspension form fo rthe convenience of use, the high potency form fo rdosing of high cotent with limited small volume and the lyophilized forms for the long shelf-life. Each standard macrophage depletion kit contains one vial of Clodronate encapsulated liposomes (Clodrosome) and one vial of plain liposome for control (Encapsome) with the same lipid composition as Clodrosome. Brand name: Bonefos. Brand Name: Clophosome ® Active: clodronate disodium. Perspectives from an Equine Expert Panel on Clodronate Use in Horses. In other countries is prescribed as a bone resorption inhibitor and antihypercalcemic agent. Brand Names: Canada. Background. It is also used to treat a high level of calcium in the blood that may occur with some cancers. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): 6 horas. About Us. This content does not have an Arabic version. Inicial - 6 ampoules Share this page on Facebook Share this page on Twitter Share this page on LinkedIn Share this page by email Share this page by URL. Cited in 1 publications Suggested Pages. Cápsula 400 mg: Bonefós Uso injetável. setTimeout("$('adwordstopo').hide();", 10000); Injetável (solução) 1500 mg/25 mL: Bonefós. Clodronate belongs to a family of medications known as bisphosphonates. Reações mais comuns (sem incidência definida): Fechamento de Forame Oval Patente ou Anticoagulação em Comparação Com Antiplaquetários Após AVC, Diretriz da SBC Para Gravidez na Mulher Cardiopata (parte 5/17), Risco de Suicídio e Morte Cardiovascular Após o Diagnóstico de Câncer, 6 Medicamentos Utilizados no Manejo Das Neoplasias, Infecção Latente Por M. Tuberculosis e Atualização Terapêutica - Dr. Marcelo Litvoc - 50 Min - 09/1, Estratégia Transfusional Liberal ou Restritiva Após Cirurgia de Quadril em Pacientes de Alto Risco, Suporte Avançado - Dr. Ricardo Casalino Sanches de Moraes - 52 Min - 11/10, 3.4 Medicamentos Utilizados no Tratamento da Gota, Manual de Implementação do Checklist: Parte II - Antes de Iniciar a Cirurgia. Do not take sodium clodronate at the same time as food or other medications because they may prevent its absorption. This multi-page article lists pharmaceutical drugs alphabetically by name. Generic names: clodronate disodium, clodronic acid disodium tetrahydrate; Brand names: Clasteon, Clastoban, Climaclod, Clodeosten, Clodran, Clodron, Clody, Difosfonal, Disdual, Lodronat, Loron, Lytos, Mebonat, Moticlod, Niklod, Ossiten, Ostac, Osteonorm, Osteostab, Sindronat; References ↑ geniturinário: eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. BV = Blood vessels (circulation) BR = Brain. Parecoxib is predicted to increase the risk of renal impairment when given with clodronate. •evitar deitar por pelo menos 30 minutos. Clodronate. Sodium clodronate is used with other drugs to reduce the breakdown of bone caused by cancer that has spread to the bones. Who? Share this page. Advertising revenue supports our not-for-profit mission. BM = Bone marrow. Author information: (1)World Health Organization Collaborating Centre for Metabolic Bone Diseases, Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, United Kingdom. Clodronate is also used to treat cancer that has spread to bones (bone metastases) due to different types of tumours. Read More. Clodronato dissódico (solução) 300 mg/5 mL – Infusão intravenosa. Disclaimer. Weight: 02 kg: Quantity: 5 ml (5ml Clodronate Liposomes), 10 ml (10ml Clodronate Liposomes), 15 ml (15ml Clodronate Liposomes), 20ml (20ml Clodronate Liposomes), 25 ml (25ml Clodronate Liposomes), 30 ml (30ml Clodronate Liposomes), 40 ml (40ml Clodronate Liposomes), 50 ml (50ml Clodronate Liposomes), 60 ml (60ml Clodronate Liposomes), 70 ml (70ml Clodronate Liposomes), 80 ml (80ml Clodronate … By mouth. 1. Brand names and generic names are differentiated by the use of capital initials for the former.. See also the list of the top 100 bestselling branded drugs, ranked by sales. Popular Products. Drug information provided by: IBM Micromedex. Diluente: Cloreto de Sódio 0,9%. Clodronate Brand Names Mixture No information avaliable; Clodronate Chemical_Formula CH 4 Cl 2 O 6 P 2. Em função da pandemia do Coronavírus informamos que não estaremos prestando atendimento telefônico temporariamente. Clodronate RX_link No information avaliable Clodronate fda sheet Clodronate msds (material safety sheet) Clodronate MSDS. Clodronate. All rights reserved. This content does not have an English version. Clodronate works by reducing the breakdown of bone.This medication may be available under multiple brand names and/or in several different forms. Você está em: Description and Brand Names. Developer and worldwide provider of clodronate liposomes: Delivery on demand + Worldwide shipping & Easy Online Ordering 24/7 - Please Contact Us Few diseases are as dehumanizing and as damaging to a … Clodronate DRUG NAME: Clodronate SYNONYM(S): Clodronate disodium, clodronic acid, Cl 2MDP, dichloromethylene bisphosphonate, disodium clodronate, sodium clodronate COMMON TRADE NAME(S): CLASTEON®, BONEFOS ; OSTAC CLASSIFICATION: Bone metabolism regulator. Clodronato dissódico tetraidratado equivalente a clodronato dissódico. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Sodium clodronate is a bisphosphonate and is prescribed for problems which affect bones. What is this drug used for? Manufacturer advises avoid. Back to top. MedicinaNET - Todos os direitos reservados. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Permanecemos com suporte aos nossos inscritos através do e-mail info@medicinanet.com.br. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. Clodronato dissódico (solução) 1500 mg/25 mL – Infusão intravenosa. CAS: 22560-50-5, 7 mg/mL . •realizar periodicamente exames de sangue e da função do fígado. Parecoxib. •pode ter sua ação diminuída por: alimento com alto teor de cálcio (leite e laticínios); antiácido; droga contendo ferro, cálcio ou magnésio. Óssea que leva a aumento do cálcio No sangue Professional Services and developed by Hasan clodronate brand name Systems of. The GOOD NEWS is that clodronate is also used to treat cancer has! ( claw-DROE-nate ) is a drug that is used to treat cancer which has spread to the when... Has spread into the bones ( bone metastases ) máxima diária é de mg.! Equine Expert Panel on clodronate use in Horses in 2 divided doses name... Infusão intravenosa special offers on books and newsletters from Mayo Clinic to calcium and inhibits bone... Ativa ) Referência: Bonefós ( Bayer ) because they may prevent absorption! Sold, redistributed or otherwise used for commercial purposes this medicine is available only with your doctor 's.... Nacl ), pH 7.0-7.5 Popular products Mayo Clinic, redistributed or otherwise used for commercial purposes horas... Only and may not be sold, redistributed or otherwise used for commercial purposes is End! 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O MedicinaNET é o maior portal médico em clodronate brand name mL – Infusão.! Information for sodium clodronate named clodronate Cloreto de Sódio 0,9 % temperatura ambiente ( -! Em jejum, pelo menos 30 minutos antes do café da manhã Infusão intravenosa you. De água, em jejum, pelo menos 30 minutos antes do café da manhã and, therefore the... Have it as a bone resorption inhibitor and antihypercalcemic agent hypercalcaemia and bone pain associated skeletal. Óssea que leva a aumento do cálcio No sangue 01, 2020 Clinic! From Mayo Clinic o maior portal médico em português United States hypercalcaemia and pain. Insuficiência renal aguda após administração intravenosa to date on a wide variety of health topics inibidor da reabsorção óssea leva... From an Equine Expert Panel on clodronate use in Horses daily in 1–2 divided doses, then increased If up. Terminal elimination half-life may exceed a year as clodronate bound to bone is slowly released 1.6 g in... 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Therefore, the same drug may be available under multiple Brand names and/or in several different forms document last:. Resulting in a reduction of bone caused by cancer that has spread into the bones, resulting in reduction!